Indiana University became the home of the National Institute of Neurological Disorders and Stroke (NINDS) biomarker repository in September of 2015. The repository, Biospecimen Exchange for Neurological Disorders (BioSEND), houses biospecimens collected through studies supported by or conducted in collaboration with NINDS. These studies include phase 2 and 3 clinical trials along with an array of studies focused on biomarkers of disease susceptibility, onset and progression. The primary goal of BioSEND is to facilitate research on a wide range of neurological and neuropsychiatric diseases and disorders. The study cohorts banked at BioSEND include Parkinson’s disease (PD), Huntington’s disease (HD), Lewy Body Dementia/ Dementia with Lewy Bodies (LBD/DLB), Frontotemporal Lobar Dementia (FTLD), and other neurological and neuropsychiatric diseases. BioSEND currently banks a variety of biospecimens, including DNA, plasma, serum, RNA, CSF, urine, and saliva from more than 30 different studies. For more information about banking with BioSEND or requesting banked samples, please contact biosend@iu.edu.
Banking by study population table
Population | DNA | Plasma | Serum | RNA | CSF | Whole Blood | Urine | Saliva | Other |
---|---|---|---|---|---|---|---|---|---|
Parkinson's Disease and Parkinsonisms | ✔ | ✔ | ✔ | ✔ | ✔ | ✔ | ✔ | ✔ | RBC-WBC pellet |
Huntington's Disease | ✔ | ✔ | ✔ | ✔ | ✔ | ✔ | ✔ | ||
Myalgic Encephalomyelitis/ Chronic Fatigue Syndrome | ✔ | ✔ | ✔ | ✔ | ✔ | ✔ | Tears, PBMC | ||
Dementia with Lewy Bodies | ✔ | ✔ | ✔ | ✔ | ✔ | ✔ | |||
Frontotemporal Lobar Dementia | ✔ | ✔ | ✔ | ✔ | ✔ | ||||
Spinocerebellar Ataxia | ✔ | ✔ | ✔ | ||||||
Traumatic Brain Injury | ✔ | ✔ | ✔ | ||||||
Control subjects | ✔ | ✔ | ✔ | ✔ | ✔ | ✔ | ✔ | ✔ | RBC-WBC pellet, Tears, PBMC |