Specimen Table

Cohort Population Genomic DNA RNA Plasma Serum Tears Urine PBMC Saliva
CFI ME/CFS Cases, Controls

Study Details

Chronic Fatigue Initiative (CFI) Study

The CFI study was a multicenter cross-sectional observational study, with the objective of establishing a well-characterized cohort of participants diagnosed with ME/CFS and controls with both clinical data and biologic specimens. The CFI was created and funded by the Hutchins Family Foundation and the clinical data and biospecimens were transferred to the National Institute of Neurological Disorders and Stroke. Investigators who request access to the CFI resource will be required to comply with the BioSEND Biospecimens User Agreement and/or the Data Use Agreement and to adhere to the Publication Policy.

Study Subjects

201 ME/CFS cases and 200 controls.

Available Data

Demographic and lifestyle data are currently available, in addition to questionnaire data to aid in characterizing ME/CFS. The questionnaires administered to the CFI study participants include the Pittsburgh Sleep Quality Index, Short Form Survey (SF-36), DePaul Symptom Questionnaire, Multidimensional Fatigue Inventory, Brief Pain Inventory, Beck Anxiety Inventory, and Depression Inventory. All data are de-identified to protect participant privacy.

Please see https://mecfs.rti.org/ for more information on ME/CFS Resources

Available Biospecimens

DNA and RNA from blood, plasma, serum, saliva, PBMC, urine, and tears.

Please contact searchMECFS@rti.org for information about available biosamples.

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