Specimen Table
| Cohort | Population | Genomic DNA | RNA | Plasma | Serum | Tears | Urine | PBMC | Saliva |
|---|---|---|---|---|---|---|---|---|---|
| CFI | ME/CFS Cases, Controls | ✔ | ✔ | ✔ | ✔ | ✔ | ✔ | ✔ | ✔ |
Study Details
Chronic Fatigue Initiative (CFI) Study
- Study Subjects
201 ME/CFS cases and 200 controls.
- Available Data
Demographic and lifestyle data are currently available, in addition to questionnaire data to aid in characterizing ME/CFS. The questionnaires administered to the CFI study participants include the Pittsburgh Sleep Quality Index, Short Form Survey (SF-36), DePaul Symptom Questionnaire, Multidimensional Fatigue Inventory, Brief Pain Inventory, Beck Anxiety Inventory, and Depression Inventory. All data are de-identified to protect participant privacy.
Please see https://mecfs.rti.org/ for more information on ME/CFS Resources
- Available Biospecimens
DNA and RNA from blood, plasma, serum, saliva, PBMC, urine, and tears.
Please contact searchMECFS@rti.org for information about available biosamples.
- Specimen Catalog
The catalog for CFI is hosted by RTI International. Use the link below to access the the searchMECFS tool to view available specimens along with a minimal clinical data set.
The CFI study was a multicenter cross-sectional observational study, with the objective of establishing a well-characterized cohort of participants diagnosed with ME/CFS and controls with both clinical data and biologic specimens. The CFI was created and funded by the Hutchins Family Foundation and the clinical data and biospecimens were transferred to the National Institute of Neurological Disorders and Stroke. Investigators who request access to the CFI resource will be required to comply with the BioSEND Biospecimens User Agreement and/or the Data Use Agreement and to adhere to the Publication Policy.