The Fox Investigation for New Discovery of Biomarkers (BioFIND)
BioFIND was an observational clinical study designed to discover and verify biomarkers of Parkinson's disease. This cross-sectional study was sponsored by MJFF with support from the National Institute of Neurological Disorders and Stroke. BioFIND followed standardized data acquisition protocols to ensure that tests and assessments conducted at multiple sites can be pooled.
Study Participants
121 patients with moderate-advanced PD and 96 healthy controls
Available Data
CLINICAL: motor, non-motor (cognitive, neurobehavioral, neuropsychological, autonomic, sleep)
BIOLOGIC: spinal fluid alpha-synuclein, amyloid-beta, tau, phosphorylated tau levels
GENETIC: whole genome sequencing, transcriptomics
Request access to the BioFIND data through LONI
Request access to the genetic data through AMP-PD
Available Biospecimens
DNA and RNA from blood, plasma, cell pellet, CSF, urine and saliva.
Please contact biosend@iu.edu for more information on how to access available data.
BioFIND is sponsored by The Michael J. Fox Foundation for Parkinson’s Research (MJFF) with support from the National Institute for Neurological Disorders and Stroke (NINDS).