NINDS Biospecimen Review Access Committees
BioSEND works with multiple disease and condition specific Biospecimen Review Access Committees. Each BRAC includes representatives from studies which banked the samples, extramural researchers with expertise in clinical research, biomarker discovery and validation, and biostatistics.
Each BRAC utilizes the same metric to assess an application, including technical feasibility, investigator expertise, statistical power, resource justification, and likelihood of the proposed research contributing important knowledge regarding disease etiology, pathogenesis, diagnosis, or treatment.
Applications are accepted on a rolling basis. Visit the specific BRAC page to access the review schedule, list of previously approved requests, and the roster of the current committee members.
Amyotrophic Lateral Sclerosis Biospecimen Resource Access Committee
The Amyotrophic Lateral Sclerosis Biospecimen Resource Access Committee (ALS BRAC) reviews applications for samples from studies of ALS, FTLD, and genetically at-risk for ALS/FTLD.
Learn more about the ALS BRACLeukodystrophy Biospecimen Review Access Committee
The Leukodystrophy Biospecimen Resource Access Committee (LD BRAC) reviews applications for biospecimens collected through The Global Leukodystrophy Initiative Clinical Trials Network (GLIA-CTN). The biospecimens represent a variety of leukodystrophies, including Aicardi–Goutières syndrome (AGS), Metachromatic Leukodystrophy (MLD), Pelizaeus Merzbacher Disease (PMD), and more.
Learn more about the LD BRACMyalgic Encephalomyelitis / Chronic Fatigue Syndrome Biospecimen Review Access Committee
The Myalgic Encephalomyelitis / Chronic Fatigue Syndrome Biospecimen Review Access Committee (ME/CFS BRAC) reviews applications for samples from studies of ME/CFS.
Learn more about the ME/CFS BRACParkinson's Disease and Related Disorders Biospecimen Review Access Committee
The Parkinson's Disease Biospecimen Review Access Committee (PD BRAC) reviews applications for samples from the PD, LBD, MSA, PSP, and other PD-related disorders banked in BioSEND. The PD BRAC also reviews requests for specimens from a number of studies funded or managed by the Michael J. Fox Foundation, including DATATOP and the LRRK2 Consortium Cohort.
Learn more about the PD BRACRepeat Expansion Disorder Biospecimen Resource Access Committee
The Repeat Expansion Disorder Biospecimen Resource Access Committee (RED BRAC) reviews applications for samples from studies of Huntington's Disease (HD), HD-related gene expansions, and Spinocerebellar Ataxia (SCA), including SCA1, SCA2, SCA3, SCA6, SCA7, SCA8, SCA10, 27B or RFC1-ataxia/CANVAS.
Learn more about the RED BRACTraumatic Brain Injury Biospecimen Review Access Committee
The Traumatic Brain Injury Biospecimen Review Access Committee (TBI BRAC) reviews applications for samples from studies of TBI, CTE, and concussion.
Learn more about the TBI BRAC